Resistance to Two Heterologous Neurotropic Oncolytic Viruses, Semliki Forest Virus and Vaccinia Virus, in Experimental Glioma

Attenuated Semliki Forest virus (SFV) may be suitable for targeting malignant glioma due to its natural neurotropism, but its replication in brain tumor cells may be restricted by innate antiviral defenses. We attempted to facilitate SFV replication in glioma cells by combining it with vaccinia viru...

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Detalhes bibliográficos
Main Authors: Vähä-Koskela, Markus J. V., Le Boeuf, Fabrice, Lemay, Chantal, De Silva, Naomi, Diallo, Jean-Simon, Cox, Julie, Becker, Michelle, Choi, Youngmin, Ananth, Abhirami, Sellers, Clara, Breton, Sophie, Roy, Dominic, Falls, Theresa, Brun, Jan, Hemminki, Akseli, Hinkkanen, Ari, Bell, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571476/
https://ncbi.nlm.nih.gov/pubmed/23221568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01609-12
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