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The autotaxin-LPA(2) GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair

In this study we characterized the effects of radiation injury on the expression and function of the autotaxin (ATX)-LPA(2) GPCR axis. In IEC-6 crypt cells and jejunum enteroids quantitative RT-PCR showed a time- and dose-dependent upregulation of lpa2 in response to γ-irradiation that was abolished...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Signal
Prif Awduron: Balogh, Andrea, Shimizu, Yoshibumi, Lee, Sue Chin, Norman, Derek D., Gangwar, Ruchika, Bavaria, Mitul, Moon, ChangSuk, Shukla, Pradeep, Rao, Radakrishna, Ray, Ramesh, Naren, Anjaparavanda P., Banerje, Souvik, Miller, Duane D., Balazs, Louisa, Pelus, Louis, Tigyi, Gabor
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514920/
https://ncbi.nlm.nih.gov/pubmed/26027517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.05.015
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