The autotaxin-LPA(2) GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair

In this study we characterized the effects of radiation injury on the expression and function of the autotaxin (ATX)-LPA(2) GPCR axis. In IEC-6 crypt cells and jejunum enteroids quantitative RT-PCR showed a time- and dose-dependent upregulation of lpa2 in response to γ-irradiation that was abolished...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Balogh, Andrea, Shimizu, Yoshibumi, Lee, Sue Chin, Norman, Derek D., Gangwar, Ruchika, Bavaria, Mitul, Moon, ChangSuk, Shukla, Pradeep, Rao, Radakrishna, Ray, Ramesh, Naren, Anjaparavanda P., Banerje, Souvik, Miller, Duane D., Balazs, Louisa, Pelus, Louis, Tigyi, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514920/
https://ncbi.nlm.nih.gov/pubmed/26027517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.05.015
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