The autotaxin-LPA(2) GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair

In this study we characterized the effects of radiation injury on the expression and function of the autotaxin (ATX)-LPA(2) GPCR axis. In IEC-6 crypt cells and jejunum enteroids quantitative RT-PCR showed a time- and dose-dependent upregulation of lpa2 in response to γ-irradiation that was abolished...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Signal
Päätekijät: Balogh, Andrea, Shimizu, Yoshibumi, Lee, Sue Chin, Norman, Derek D., Gangwar, Ruchika, Bavaria, Mitul, Moon, ChangSuk, Shukla, Pradeep, Rao, Radakrishna, Ray, Ramesh, Naren, Anjaparavanda P., Banerje, Souvik, Miller, Duane D., Balazs, Louisa, Pelus, Louis, Tigyi, Gabor
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514920/
https://ncbi.nlm.nih.gov/pubmed/26027517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.05.015
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