Autotaxin, LPA Receptors (1 and 5) Exert Disparate Functions in Tumor Cells Versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis

Autotaxin (ENPP2/ATX) and lysophosphatidic acid (LPA) receptors represent two key players in regulating cancer progression. The present study sought to understand the mechanistic role of LPA G protein-coupled receptors (GPCR), not only in the tumor cells but also in stromal cells of the tumor microe...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Lee, Sue-Chin, Fujiwara, Yuko, Liu, Jianxiong, Yue, Junming, Shimizu, Yoshibumi, Norman, Derek D., Wang, Yaohong, Tsukahara, Ryoko, Szabo, Erzsebet, Patil, Renukadevi, Banerjee, Souvik, Miller, Duane D., Balazs, Louisa, Ghosh, Manik C., Waters, Christopher M., Oravecz, Tamas, Tigyi, Gabor J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297753/
https://ncbi.nlm.nih.gov/pubmed/25158955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0263
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