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SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity
The HIV-1 restriction factor SAMHD1 is a tetrameric enzyme activated by guanine nucleotides with dNTP triphosphate hydrolase activity (dNTPase). In addition to this established activity, there have been a series of conflicting reports as to whether the enzyme also possesses single-stranded DNA and/o...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513882/ https://ncbi.nlm.nih.gov/pubmed/26101257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv633 |
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