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Single-Molecule Force Spectroscopy Studies of APOBEC3A–Single-Stranded DNA Complexes

APOBEC3A (A3A) inhibits the replication of a range of viruses and transposons and might also play a role in carcinogenesis. It is a single-domain deaminase enzyme that interacts with single-stranded DNA (ssDNA) and converts cytidines to uridines within specific trinucleotide contexts. Although there...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Shlyakhtenko, Luda S., Dutta, Samrat, Li, Ming, Harris, Reuben S., Lyubchenko, Yuri L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932870/
https://ncbi.nlm.nih.gov/pubmed/27182892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00214
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