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Single-Molecule Force Spectroscopy Studies of APOBEC3A–Single-Stranded DNA Complexes
APOBEC3A (A3A) inhibits the replication of a range of viruses and transposons and might also play a role in carcinogenesis. It is a single-domain deaminase enzyme that interacts with single-stranded DNA (ssDNA) and converts cytidines to uridines within specific trinucleotide contexts. Although there...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932870/ https://ncbi.nlm.nih.gov/pubmed/27182892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00214 |
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