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APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies

APOBEC3G (A3G) protein has antiviral activity against HIV and other pathogenic retroviruses. A3G has two domains: a catalytic C-terminal domain (CTD) that deaminates cytidine, and a N-terminal domain (NTD) that binds to ssDNA. Although abundant information exists about the biological activities of A...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Shlyakhtenko, Luda S., Dutta, Samrat, Banga, Jaspreet, Li, Ming, Harris, Reuben S., Lyubchenko, Yuri L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621513/
https://ncbi.nlm.nih.gov/pubmed/26503602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15648
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