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Nanoscale Characterization of Interaction of APOBEC3G with RNA

The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of the HIV-1 virus in the absence of viral infectivity factor (Vif). The molecular mechanism of A3G antiviral activity is primarily attributed to deamination of single-stranded DNA (ssDNA); however, the nondeamination mechanism also c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Pan, Yangang, Sun, Zhiqiang, Maiti, Atanu, Kanai, Tapan, Matsuo, Hiroshi, Li, Ming, Harris, Reuben S., Shlyakhtenko, Luda S., Lyubchenko, Yuri L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712427/
https://ncbi.nlm.nih.gov/pubmed/28029777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01189
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