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Nanoscale Characterization of Interaction of APOBEC3G with RNA
The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of the HIV-1 virus in the absence of viral infectivity factor (Vif). The molecular mechanism of A3G antiviral activity is primarily attributed to deamination of single-stranded DNA (ssDNA); however, the nondeamination mechanism also c...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5712427/ https://ncbi.nlm.nih.gov/pubmed/28029777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01189 |
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