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A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase

Sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) is a recently discovered enzyme that plays a central role in nucleotide metabolism and innate immunity. SAMHD1 has deoxyribonucleoside triphosphate (dNTP) triphosphohydrolase activity that depletes the dNTP substrates r...

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Détails bibliographiques
Publié dans:J Biomol Screen
Auteurs principaux: Seamon, Kyle J., Stivers, James T.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475474/
https://ncbi.nlm.nih.gov/pubmed/25755265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115575150
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