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A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase
Sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) is a recently discovered enzyme that plays a central role in nucleotide metabolism and innate immunity. SAMHD1 has deoxyribonucleoside triphosphate (dNTP) triphosphohydrolase activity that depletes the dNTP substrates r...
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| Pubblicato in: | J Biomol Screen |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475474/ https://ncbi.nlm.nih.gov/pubmed/25755265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115575150 |
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