Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure

Pathological cardiac hypertrophy often leads to heart failure. Activation of autophagy has been shown in pathological hypertrophic hearts. Autophagy is regulated positively by Class III phosphoinositide 3-kinase (PI3K). However, it is unknown whether Class III PI3K plays a role in the transition of...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yu, Peng, Zhang, Yangyang, Li, Chuanfu, Li, Yuehua, Jiang, Surong, Zhang, Xiaojin, Ding, Zhengnian, Tu, Fei, Wu, Jun, Gao, Xiang, Li, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511367/
https://ncbi.nlm.nih.gov/pubmed/25851780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12547
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