Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure

Pathological cardiac hypertrophy often leads to heart failure. Activation of autophagy has been shown in pathological hypertrophic hearts. Autophagy is regulated positively by Class III phosphoinositide 3-kinase (PI3K). However, it is unknown whether Class III PI3K plays a role in the transition of...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Yu, Peng, Zhang, Yangyang, Li, Chuanfu, Li, Yuehua, Jiang, Surong, Zhang, Xiaojin, Ding, Zhengnian, Tu, Fei, Wu, Jun, Gao, Xiang, Li, Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511367/
https://ncbi.nlm.nih.gov/pubmed/25851780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12547
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