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Regulation of Mammalian Autophagy by Class II and III PI 3-Kinases through PI3P Synthesis
Synthesis of phosphatidylinositol-3-phosphate (PI3P) by Vps34, a class III phosphatidylinositol 3-kinase (PI3K), is critical for the initial steps of autophagosome (AP) biogenesis. Although Vps34 is the sole source of PI3P in budding yeast, mammalian cells can produce PI3P through alternate pathways...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789715/ https://ncbi.nlm.nih.gov/pubmed/24098492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076405 |
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