Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

A critical regulator of autophagy is the Class III PI3K Vps34 (also called PIK3C3). Although Vps34 is known to play an essential role in autophagy in yeast, its role in mammals remains elusive. To elucidate the physiological function of Vps34 and to determine its precise role in autophagy, we have g...

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Detalhes bibliográficos
Main Authors: Jaber, Nadia, Dou, Zhixun, Chen, Juei-Suei, Catanzaro, Joseph, Jiang, Ya-Ping, Ballou, Lisa M., Selinger, Elzbieta, Ouyang, Xiaosen, Lin, Richard Z., Zhang, Jianhua, Zong, Wei-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277541/
https://ncbi.nlm.nih.gov/pubmed/22308354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112848109
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