Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

A critical regulator of autophagy is the Class III PI3K Vps34 (also called PIK3C3). Although Vps34 is known to play an essential role in autophagy in yeast, its role in mammals remains elusive. To elucidate the physiological function of Vps34 and to determine its precise role in autophagy, we have g...

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Bibliografiske detaljer
Main Authors: Jaber, Nadia, Dou, Zhixun, Chen, Juei-Suei, Catanzaro, Joseph, Jiang, Ya-Ping, Ballou, Lisa M., Selinger, Elzbieta, Ouyang, Xiaosen, Lin, Richard Z., Zhang, Jianhua, Zong, Wei-Xing
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277541/
https://ncbi.nlm.nih.gov/pubmed/22308354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112848109
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