The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila

Degradation of cytoplasmic components by autophagy requires the class III phosphatidylinositol 3 (PI(3))–kinase Vps34, but the mechanisms by which this kinase and its lipid product PI(3) phosphate (PI(3)P) promote autophagy are unclear. In mammalian cells, Vps34, with the proautophagic tumor suppres...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Juhász, Gábor, Hill, Jahda H., Yan, Ying, Sass, Miklós, Baehrecke, Eric H., Backer, Jonathan M., Neufeld, Thomas P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2008
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386105/
https://ncbi.nlm.nih.gov/pubmed/18474623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712051
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