The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila

Degradation of cytoplasmic components by autophagy requires the class III phosphatidylinositol 3 (PI(3))–kinase Vps34, but the mechanisms by which this kinase and its lipid product PI(3) phosphate (PI(3)P) promote autophagy are unclear. In mammalian cells, Vps34, with the proautophagic tumor suppres...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Juhász, Gábor, Hill, Jahda H., Yan, Ying, Sass, Miklós, Baehrecke, Eric H., Backer, Jonathan M., Neufeld, Thomas P.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386105/
https://ncbi.nlm.nih.gov/pubmed/18474623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712051
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki