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The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
Degradation of cytoplasmic components by autophagy requires the class III phosphatidylinositol 3 (PI(3))–kinase Vps34, but the mechanisms by which this kinase and its lipid product PI(3) phosphate (PI(3)P) promote autophagy are unclear. In mammalian cells, Vps34, with the proautophagic tumor suppres...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386105/ https://ncbi.nlm.nih.gov/pubmed/18474623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712051 |
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