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Activation of Gα(q) in cardiomyocytes increases Vps34 activity and stimulates autophagy

Receptors that activate the heterotrimeric G protein Gα(q) are thought to play a role in the development of heart failure. Dysregulation of autophagy occurs in some pathological cardiac conditions including heart failure, but whether Gα(q) is involved in this process is unknown. We used a cardiomyoc...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Liu, Shengnan, Jiang, Ya-Ping, Ballou, Lisa M., Zong, Wei-Xing, Lin, Richard Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382807/
https://ncbi.nlm.nih.gov/pubmed/28376509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000461
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