HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism

Endothelial damage is a critical mediator of myocardial ischemia/reperfusion (I/R) injury. HSPA12B is an endothelial-cell-specifically expressed heat shock protein. However, the roles of HSPA12B in acute myocardial I/R injury is unknown. Here we reported that myocardial I/R upregulated HSPA12B expre...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kong, Qiuyue, Dai, Leyang, Wang, Yana, Zhang, Xiaojin, Li, Chuanfu, Jiang, Surong, Li, Yuehua, Ding, Zhengnian, Liu, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028890/
https://ncbi.nlm.nih.gov/pubmed/27644317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33636
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