RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. Two classes of piRNAs—primary and secondary—are defined by their mechanisms of biogenesis. Primary piRNAs are processed directly from transcripts of piRNA cluster loci, whereas secondary piRNAs...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Wasik, Kaja A., Tam, Oliver H., Knott, Simon R., Falciatori, Ilaria, Hammell, Molly, Vagin, Vasily V., Hannon, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511215/
https://ncbi.nlm.nih.gov/pubmed/26115953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265215.115
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