Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members

In germ cells, Piwi proteins interact with a specific class of small noncoding RNAs, piwi-interacting RNAs (piRNAs). Together, these form a pathway that represses transposable elements, thus safeguarding germ cell genomes. Basic models describe the overall operation of piRNA pathways. However, the p...

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Bibliografiske detaljer
Main Authors: Vagin, Vasily V., Wohlschlegel, James, Qu, Jun, Jonsson, Zophonias, Huang, Xinhua, Chuma, Shinichiro, Girard, Angelique, Sachidanandam, Ravi, Hannon, Gregory J., Aravin, Alexei A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720255/
https://ncbi.nlm.nih.gov/pubmed/19584108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1814809
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