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RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. Two classes of piRNAs—primary and secondary—are defined by their mechanisms of biogenesis. Primary piRNAs are processed directly from transcripts of piRNA cluster loci, whereas secondary piRNAs...

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Vydáno v:Genes Dev
Hlavní autoři: Wasik, Kaja A., Tam, Oliver H., Knott, Simon R., Falciatori, Ilaria, Hammell, Molly, Vagin, Vasily V., Hannon, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511215/
https://ncbi.nlm.nih.gov/pubmed/26115953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265215.115
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