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Multiple roles for Piwi in silencing Drosophila transposons

Silencing of transposons in the Drosophila ovary relies on three Piwi family proteins—Piwi, Aubergine (Aub), and Ago3—acting in concert with their small RNA guides, the Piwi-interacting RNAs (piRNAs). Aub and Ago3 are found in the germ cell cytoplasm, where they function in the ping-pong cycle to co...

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Detalhes bibliográficos
Main Authors: Rozhkov, Nikolay V., Hammell, Molly, Hannon, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589557/
https://ncbi.nlm.nih.gov/pubmed/23392609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.209767.112
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