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Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury

Axonal growth and neuronal rewiring facilitate functional recovery after spinal cord injury. Known interventions that promote neural repair remain limited in their functional efficacy. To understand genetic determinants of mammalian CNS axon regeneration, we completed an unbiased RNAi gene-silencing...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Zou, Yixiao, Stagi, Massimiliano, Wang, Xingxing, Yigitkanli, Kazim, Siegel, Chad S., Nakatsu, Fubito, Cafferty, William B. J., Strittmatter, Stephen M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510284/
https://ncbi.nlm.nih.gov/pubmed/26203138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1718-15.2015
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