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Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway
The recruitment of inositol phosphatases to endocytic membranes mediates dephosphorylation of PI(4,5)P(2), a phosphoinositide concentrated in the plasma membrane, and prevents its accumulation on endosomes. The importance of the conversion of PI(4,5)P(2) to PtdIns during endocytosis is demonstrated...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395491/ https://ncbi.nlm.nih.gov/pubmed/25869668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409064 |
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