Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury

Axonal growth and neuronal rewiring facilitate functional recovery after spinal cord injury. Known interventions that promote neural repair remain limited in their functional efficacy. To understand genetic determinants of mammalian CNS axon regeneration, we completed an unbiased RNAi gene-silencing...

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Vydáno v:J Neurosci
Hlavní autoři: Zou, Yixiao, Stagi, Massimiliano, Wang, Xingxing, Yigitkanli, Kazim, Siegel, Chad S., Nakatsu, Fubito, Cafferty, William B. J., Strittmatter, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510284/
https://ncbi.nlm.nih.gov/pubmed/26203138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1718-15.2015
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