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Silencing of Essential Genes within a Highly Coordinated Operon in Escherichia coli

Essential bacterial genes located within operons are particularly challenging to study independently because of coordinated gene expression and the nonviability of knockout mutants. Essentiality scores for many operon genes remain uncertain. Antisense RNA (asRNA) silencing or in-frame gene disruptio...

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Foilsithe in:Appl Environ Microbiol
Main Authors: Goh, Shan, Hohmeier, Angela, Stone, Timothy C., Offord, Victoria, Sarabia, Francisco, Garcia-Ruiz, Cristina, Good, Liam
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510190/
https://ncbi.nlm.nih.gov/pubmed/26070674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01444-15
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