Topologically associating domains and their long-range contacts are established during early G1 coincident with the establishment of the replication-timing program

Mammalian genomes are partitioned into domains that replicate in a defined temporal order. These domains can replicate at similar times in all cell types (constitutive) or at cell type-specific times (developmental). Genome-wide chromatin conformation capture (Hi-C) has revealed sub-megabase topolog...

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Bibliographic Details
Published in:Genome Res
Main Authors: Dileep, Vishnu, Ay, Ferhat, Sima, Jiao, Vera, Daniel L., Noble, William S., Gilbert, David M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509995/
https://ncbi.nlm.nih.gov/pubmed/25995270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.183699.114
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