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Single-cell replication profiling to measure stochastic variation in mammalian replication timing

Mammalian DNA replication is regulated via multi-replicon segments that replicate in a defined temporal order during S-phase. Further, early/late replication of RDs corresponds to active/inactive chromatin interaction compartments. Although replication origins are selected stochastically, variation...

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Vydáno v:Nat Commun
Hlavní autoři: Dileep, Vishnu, Gilbert, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789892/
https://ncbi.nlm.nih.gov/pubmed/29382831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02800-w
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