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The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase

We have examined the dynamics of nuclear repositioning and the establishment of a replication timing program for the actively transcribed dihydrofolate reductase (DHFR) locus and the silent β-globin gene locus in Chinese hamster ovary cells. The DHFR locus was internally localized and replicated ear...

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Detalhes bibliográficos
Main Authors: Li, Feng, Chen, Jianhua, Izumi, Masako, Butler, Mark C., Keezer, Susan M., Gilbert, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1255917/
https://ncbi.nlm.nih.gov/pubmed/11470818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200104043
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