Developmental regulation of DNA replication timing at the human β globin locus

The human β globin locus replicates late in most cell types, but becomes early replicating in erythroid cells. Using FISH to map DNA replication timing around the endogenous β globin locus and by applying a genetic approach in transgenic mice, we have demonstrated that both the late and early replic...

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Detalhes bibliográficos
Main Authors: Simon, Itamar, Tenzen, Toyoaki, Mostoslavsky, Raul, Fibach, Eitan, Lande, Laura, Milot, Eric, Gribnau, Joost, Grosveld, Frank, Fraser, Peter, Cedar, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125288/
https://ncbi.nlm.nih.gov/pubmed/11689454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6150
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