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Requirements for utilization of CREB binding protein by hypersensitive site two of the β-globin locus control region
Strong transactivation of the β-globin genes is conferred by the β-globin locus control region (LCR), which consists of four erythroid-specific DNase I hypersensitive sites (HS1–HS4). HS2 has a powerful enhancer activity dependent upon tandem binding sites for the erythroid cell- and megakaryocyte-s...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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Oxford University Press
2002
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC101831/ https://ncbi.nlm.nih.gov/pubmed/11917012 |
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