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Form and function of topologically associating genomic domains in budding yeast

The genome of metazoan cells is organized into topologically associating domains (TADs) that have similar histone modifications, transcription level, and DNA replication timing. Although similar structures appear to be conserved in fission yeast, computational modeling and analysis of high-throughpu...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Eser, Umut, Chandler-Brown, Devon, Ay, Ferhat, Straight, Aaron F., Duan, Zhijun, Noble, William Stafford, Skotheim, Jan M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393236/
https://ncbi.nlm.nih.gov/pubmed/28348222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612256114
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