Topologically associating domains are stable units of replication-timing regulation

Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program(1). In mammals, replication timing is cell-type-specific with at least half the genome switching replication timing during development, primarily in units of 400–800 kilobases (‘replication domains’), whose...

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Publicado no:Nature
Main Authors: Pope, Benjamin D., Ryba, Tyrone, Dileep, Vishnu, Yue, Feng, Wu, Weisheng, Denas, Olgert, Vera, Daniel L., Wang, Yanli, Hansen, R. Scott, Canfield, Theresa K., Thurman, Robert E., Cheng, Yong, Gülsoy, Günhan, Dennis, Jonathan H., Snyder, Michael P., Stamatoyannopoulos, John A., Taylor, James, Hardison, Ross C., Kahveci, Tamer, Ren, Bing, Gilbert, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251741/
https://ncbi.nlm.nih.gov/pubmed/25409831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13986
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