Topologically associating domains are stable units of replication-timing regulation

Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program(1). In mammals, replication timing is cell-type-specific with at least half the genome switching replication timing during development, primarily in units of 400–800 kilobases (‘replication domains’), whose...

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Published in:Nature
Main Authors: Pope, Benjamin D., Ryba, Tyrone, Dileep, Vishnu, Yue, Feng, Wu, Weisheng, Denas, Olgert, Vera, Daniel L., Wang, Yanli, Hansen, R. Scott, Canfield, Theresa K., Thurman, Robert E., Cheng, Yong, Gülsoy, Günhan, Dennis, Jonathan H., Snyder, Michael P., Stamatoyannopoulos, John A., Taylor, James, Hardison, Ross C., Kahveci, Tamer, Ren, Bing, Gilbert, David M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251741/
https://ncbi.nlm.nih.gov/pubmed/25409831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13986
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