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Inside-out Ca(2+) signalling prompted by STIM1 conformational switch
Store-operated Ca(2+) entry mediated by STIM1 and ORAI1 constitutes one of the major Ca(2+) entry routes in mammalian cells. The molecular choreography of STIM1–ORAI1 coupling is initiated by endoplasmic reticulum (ER) Ca(2+) store depletion with subsequent oligomerization of the STIM1 ER-luminal do...
Gorde:
Argitaratua izan da: | Nat Commun |
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Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Nature Pub. Group
2015
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509486/ https://ncbi.nlm.nih.gov/pubmed/26184105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8826 |
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