Bcl-2 expression during T-cell development: early loss and late return occur at specific stages of commitment to differentiation and survival.
During T-cell development CD3-CD4-CD8- (double-negative) thymocytes proliferative and produce an enormous number of CD3loCD4+CD8+ (double-positive) thymocytes which are destined to die intrathymically unless rescued by positive selection. Those which survive become mature CD3hiCD4/8+ (single-positiv...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1994
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7938012/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10685 |
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