CD8 Co-receptor promotes susceptibility of CD8(+) T cells to transforming growth factor-β (TGF-β)-mediated suppression

CD8(+) T cell function depends on a finely orchestrated balance of activation/suppression signals. While the stimulatory role of the CD8 co-receptor and pleiotropic capabilities of TGF-β have been studied individually, the influence of CD8 co-receptor on TGF-β function in CD8(+) T cells is unknown....

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Bibliographic Details
Published in:Cancer Immunol Immunother
Main Authors: Zloza, Andrew, Jagoda, Michael C., Lyons, Gretchen E., Graves, Michael C., Kohlhapp, Frederick J., O’Sullivan, Jeremy A., Lacek, Andrew T., Nishimura, Michael I., Guevara-Patiño, José A.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2010
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Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507403/
https://ncbi.nlm.nih.gov/pubmed/21193909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0962-6
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