CD8+ T cells Sabotage their own Memory Potential through IFN-γ-dependent modification of the IL-12/IL-15Rα axis on Dendritic Cells

Míreanna Comhchosúla

• Development of Tumor-infiltrating CD8+ T cell Memory Precursor Effector Cells (MPECs) and Anti-melanoma Memory Responses are the Result of Vaccination and TGF-β Blockade During the Perioperative Period of Tumor Resection
  le: Bellavance, Emily C., et al.
  Foilsithe: (2011)
• Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression
  le: O'Sullivan, Jeremy A., et al.
  Foilsithe: (2011)
• CD8 Co-receptor promotes susceptibility of CD8(+) T cells to transforming growth factor-β (TGF-β)-mediated suppression
  le: Zloza, Andrew, et al.
  Foilsithe: (2010)
• NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses
  le: Zloza, Andrew, et al.
  Foilsithe: (2012)
• Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-γ limits IL-17–mediated autoimmune inflammation
  le: Murugaiyan, Gopal, et al.
  Foilsithe: (2010)