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CD8 Co-receptor promotes susceptibility of CD8(+) T cells to transforming growth factor-β (TGF-β)-mediated suppression
CD8(+) T cell function depends on a finely orchestrated balance of activation/suppression signals. While the stimulatory role of the CD8 co-receptor and pleiotropic capabilities of TGF-β have been studied individually, the influence of CD8 co-receptor on TGF-β function in CD8(+) T cells is unknown....
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Publié dans: | Cancer Immunol Immunother |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Springer-Verlag
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507403/ https://ncbi.nlm.nih.gov/pubmed/21193909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0962-6 |
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