Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A

Immunotherapy with allogeneic natural killer (NK) cells offers therapeutic perspectives for multiple myeloma patients. Here, we aimed to refine NK cell therapy by evaluation of the relevance of HLA-class I and HLA-E for NK anti-myeloma reactivity. We show that HLA-class I was strongly expressed on t...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Sarkar, Subhashis, van Gelder, Michel, Noort, Willy, Xu, Yunping, Rouschop, Kasper M. A., Groen, Richard, Schouten, Harry C., Tilanus, Marcel G. J., Germeraad, Wilfred T. V., Martens, Anton C. M., Bos, Gerard M. J., Wieten, Lotte
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506464/
https://ncbi.nlm.nih.gov/pubmed/25920521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1694-4
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