Tuning Natural Killer Cell Anti-multiple Myeloma Reactivity by Targeting Inhibitory Signaling via KIR and NKG2A

Natural killer (NK) cells are attractive candidates for allogeneic cell-based immunotherapy due to their potent antitumor effector function and good safety profile. NK cells express killer immunoglobulin-like receptors (KIRs) and the NKG2A receptor important for NK cells education as well as providi...

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Vydáno v:Front Immunol
Hlavní autoři: Mahaweni, Niken M., Ehlers, Femke A. I., Bos, Gerard M. J., Wieten, Lotte
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288976/
https://ncbi.nlm.nih.gov/pubmed/30564241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02848
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