Activated Natural Killer Cells Withstand the Relatively Low Glucose Concentrations Found in the Bone Marrow of Multiple Myeloma Patients

Infusion of ex vivo expanded and cytokine-activated natural killer (NK) cells is a promising alternative way to treat multiple myeloma (MM). However, the tumor microenvironment (TME) may suppress their function. While reduced glucose availability is a TME hallmark of many solid tumors, glucose level...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ehlers, Femke A. I., Mahaweni, Niken M., Olieslagers, Timo I., Bos, Gerard M. J., Wieten, Lotte
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174784/
https://ncbi.nlm.nih.gov/pubmed/34094908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.622896
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