Optimal selection of natural killer cells to kill myeloma: the role of HLA-E and NKG2A

Immunotherapy with allogeneic natural killer (NK) cells offers therapeutic perspectives for multiple myeloma patients. Here, we aimed to refine NK cell therapy by evaluation of the relevance of HLA-class I and HLA-E for NK anti-myeloma reactivity. We show that HLA-class I was strongly expressed on t...

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Dettagli Bibliografici
Pubblicato in:Cancer Immunol Immunother
Autori principali: Sarkar, Subhashis, van Gelder, Michel, Noort, Willy, Xu, Yunping, Rouschop, Kasper M. A., Groen, Richard, Schouten, Harry C., Tilanus, Marcel G. J., Germeraad, Wilfred T. V., Martens, Anton C. M., Bos, Gerard M. J., Wieten, Lotte
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506464/
https://ncbi.nlm.nih.gov/pubmed/25920521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1694-4
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