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Targeting pancreatic cancer metastasis by inhibition of Vav1, a driver of tumor cell invasion

Pancreatic cancer, one of the most lethal forms of human cancer, is largely resistant to many conventional chemotherapeutic agents. While many therapeutic approaches focus on tumor growth, metastasis is a primary factor contributing to lethality. Therefore, novel therapies to target metastatic invas...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Razidlo, Gina L., Magnine, Christopher, Sletten, Arthur C., Hurley, Rachel M., Almada, Luciana L., Fernandez-Zapico, Martin E., Ji, Baoan, McNiven, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506209/
https://ncbi.nlm.nih.gov/pubmed/25977335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3103
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