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Vav1 as a Central Regulator of Invadopodia Assembly

Invadopodia are protrusive structures used by tumor cells for degradation of the extracellular matrix to promote invasion [1]. Invadopodia formation and function are regulated by cytoskeletal remodeling pathways and the oncogenic kinase Src. The guanine nucleotide exchange factor Vav1, which is an a...

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Autors principals: Razidlo, Gina L., Schroeder, Barbara, Chen, Jing, Billadeau, Daniel D., McNiven, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917499/
https://ncbi.nlm.nih.gov/pubmed/24332539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.11.013
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