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Targeting pancreatic cancer metastasis by inhibition of Vav1, a driver of tumor cell invasion

Pancreatic cancer, one of the most lethal forms of human cancer, is largely resistant to many conventional chemotherapeutic agents. While many therapeutic approaches focus on tumor growth, metastasis is a primary factor contributing to lethality. Therefore, novel therapies to target metastatic invas...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Razidlo, Gina L., Magnine, Christopher, Sletten, Arthur C., Hurley, Rachel M., Almada, Luciana L., Fernandez-Zapico, Martin E., Ji, Baoan, McNiven, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506209/
https://ncbi.nlm.nih.gov/pubmed/25977335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3103
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