The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28

WTX encodes a tumor suppressor implicated in the pediatric kidney cancer Wilms tumor and in mesenchymal differentiation with potentially distinct functions in the cytoplasm, at the plasma membrane, and in the nucleus. Although modulating components of the WNT signaling pathway is a proposed function...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Kim, Woo Jae, Wittner, Ben S., Amzallag, Arnaud, Brannigan, Brian W., Ting, David T., Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505506/
https://ncbi.nlm.nih.gov/pubmed/25882849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631945
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