The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28

WTX encodes a tumor suppressor implicated in the pediatric kidney cancer Wilms tumor and in mesenchymal differentiation with potentially distinct functions in the cytoplasm, at the plasma membrane, and in the nucleus. Although modulating components of the WNT signaling pathway is a proposed function...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Kim, Woo Jae, Wittner, Ben S., Amzallag, Arnaud, Brannigan, Brian W., Ting, David T., Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505506/
https://ncbi.nlm.nih.gov/pubmed/25882849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631945
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