The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28

WTX encodes a tumor suppressor implicated in the pediatric kidney cancer Wilms tumor and in mesenchymal differentiation with potentially distinct functions in the cytoplasm, at the plasma membrane, and in the nucleus. Although modulating components of the WNT signaling pathway is a proposed function...

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Vydáno v:J Biol Chem
Hlavní autoři: Kim, Woo Jae, Wittner, Ben S., Amzallag, Arnaud, Brannigan, Brian W., Ting, David T., Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505506/
https://ncbi.nlm.nih.gov/pubmed/25882849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631945
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