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The WTX tumor suppressor enhances p53 acetylation 9 by CBP/p300

WTX encodes a tumor suppressor, frequently inactivated in Wilms tumor, with both plasma membrane and nuclear localization. WTX has been implicated in β-catenin turnover, but its effect on nuclear proteins is unknown. We report an interaction between WTX and p53, derived from the unexpected observati...

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Detalhes bibliográficos
Main Authors: Kim, Woo Jae, Rivera, Miguel N., Coffman, Erik J., Haber, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310179/
https://ncbi.nlm.nih.gov/pubmed/22285752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.025
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